Carboxylic acids and derivatives
Selleck Chemical LLC Sulfamethazine Sodium Salt S5210-25mg
Sulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry
Bioworld Succinic Acid, Disodium Salt Hexahydrate Reagent Grade, 1 kg
Synonym: Butanedioic acid disodium salt, Succinic acid disodium salt Appearance: SolidBoiling Point : 300 °CRTECS Number: WM7751000
![Medchemexpress LLC 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-benz[de]isoquinoline | 2080306-23-4 | MFCD30480933 | 99.4% | 429.47 g·mol⁻¹ | C25H23N3O4 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000241016.png-250.jpg)
Medchemexpress LLC 2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-benz[de]isoquinoline | 2080306-23-4 | MFCD30480933 | 99.4% | 429.47 g·mol⁻¹ | C25H23N3O4 | 1 ML
BAY-299 is a small-molecule chemical probe that selectively targets bromodomain-containing proteins, inhibiting BRPF2 (BRD1) and the second bromodomains of TAF1 and TAF1L. It is used in biochemical and cell-based research to probe bromodomain function and epigenetic regulation.
- Potent dual inhibitor with reported IC50s: BRPF2 BD 67 nM, TAF1 BD2 8 nM, TAF1L BD2 106 nM.
- High purity as supplied: 99.4% (HPLC).
- Chemical formula C25H23N3O4 and molecular weight 429.47 g·mol⁻¹.
- Available as a 10 mM solution in DMSO (1 mL) and as solid quantities from 5 mg to 500 mg.
- Supplied with SMILES and structure information for computational and cheminformatics use.
Medchemexpress LLC Rp-cAMPS sodium salt | 142439-94-9 | 99.7% | 367.25 g/mol | C10H11N5NaO5PS | 25 MG
Rp-cAMPS sodium salt is a stereospecific, non-hydrolyzable cyclic AMP analog that competitively antagonizes cAMP-dependent protein kinase A (PKA) isoforms I and II. It is used as a biochemical tool to probe cAMP/PKA signaling pathways in enzyme inhibition and cell signaling research.
- Resistant to hydrolysis by phosphodiesterases.
- Competitive antagonist of cAMP-dependent PKA I and II (Ki ≈ 12.5 μM and 4.5 μM).
- High reported purity (≈99.7%).
- Available as small solid quantities and as a DMSO solution.
- Stable when stored sealed at -20°C; in solution, store at -80°C up to 6 months.
- Suitable for biochemical assays and cell signaling studies.
Apexbio Technology LLC Rigosertib sodium salt 1225497-78-8 100mg
Rigosertib sodium salt (CAS 1225497-78-8) is a selective inhibitor targeting Polo-like kinase 1 (PLK1) with reported IC50 approximately 9 nM The compound notably decreases proliferation of cancer cell lines demonstrating nanomolar IC50 values in HeLa (115 nM) and C33A (45 nM) cells whereas normal cells (e g BJ and Ect1/E6E7) remain largely unaffected At concentrations exceeding 0 5 M rigosertib robustly induces G2/M phase arrest in cancer cells without significant cell cycle disruption at lower doses Additionally in vivo studies suggest its potential as a radiosensitizer in cervical carcinoma research
Medchemexpress LLC HQ-415 | 430462-93-4 | 98.1% | 415.48 | C25H25N3O3 | 10 MG
HQ-415 is a biologically active metal chelator related to clioquinol, reported to have an EC50 of 15 μM. It is supplied as a research reagent for laboratory studies of metal chelation and related biochemical assays.
- Biologically active metal chelator related to clioquinol.
- Reported EC50 15 μM.
- Molecular formula C25H25N3O3; molecular weight 415.48.
- Purity 98.1%.
- Available in small research pack sizes: 1 mg, 5 mg, 10 mg.
- Storage: powder at -20°C for long-term; in solvent store at -80°C when possible.
- For research use only; not for human or animal therapeutic use.
Apexbio Technology LLC NB-598 Maleate 155294-62-5 10mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
Medchemexpress LLC Velnacrine maleate | 118909-22-1 | HY-W011246 | 98.0% | 330.34 | 100 MG
Velnacrine maleate (HP 029) is an orally active cholinesterase inhibitor that can be used for the research of Alzheimer's disease.
- Orally active
- Cholinesterase inhibitor
- Used for research of Alzheimer's disease
Medchemexpress LLC Tegaserod (maleate) | 189188-57-6 | 99.9% | C20H27N5O5 | 1 ML
Tegaserod maleate is an orally active serotonin receptor 4 (HTR4) agonist and a 5-HT2B receptor antagonist. It demonstrates anti-tumor activity by inducing tumor cell apoptosis and blunting PI3K/Akt/mTOR signaling. It is also being researched for its potential in treating irritable bowel syndrome (IBS) and diabetic gastropathy.
- Potent agonist of 5-HT4 receptor
- Antagonist of 5-HT2B receptor
- Induces tumor cell apoptosis
- Blunts PI3K/Akt/mTOR signaling
- Decreases S6 phosphorylation
- Accelerates gastric emptying rate
Apexbio Technology LLC Indacaterol Maleate 753498-25-8 50mg
Indacaterol Maleate (CAS 753498-25-8) is a synthetic ultra-long-acting agonist of -adrenoceptors exhibiting a pK sub i /sub value of 7 36 for these targets By selectively activating sub 2 /sub -adrenergic receptors it modulates intracellular signaling pathways that induce bronchodilation and smooth muscle relaxation Indacaterol Maleate is widely utilized in biomedical research to investigate -adrenergic signaling mechanisms pulmonary pharmacology and novel therapeutic interventions for respiratory disorders involving airway constriction